{"id":2474,"date":"2024-03-01T23:17:00","date_gmt":"2024-03-01T22:17:00","guid":{"rendered":"https:\/\/dbis.ibp.cz\/?p=2474"},"modified":"2024-06-27T23:26:45","modified_gmt":"2024-06-27T21:26:45","slug":"new-publication-chitosan-dialdehyde-cellulose-hydrogels-with-covalently-anchored-polypyrrole-novel-conductive-antibacterial-antioxidant-immunomodulatory-and-anti-inflammatory-materials","status":"publish","type":"post","link":"https:\/\/dbis.ibp.cz\/index.php\/2024\/03\/01\/new-publication-chitosan-dialdehyde-cellulose-hydrogels-with-covalently-anchored-polypyrrole-novel-conductive-antibacterial-antioxidant-immunomodulatory-and-anti-inflammatory-materials\/","title":{"rendered":"New publication: Chitosan\/dialdehyde cellulose hydrogels with covalently anchored polypyrrole: Novel conductive, antibacterial, antioxidant, immunomodulatory, and anti-inflammatory materials"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"2474\" class=\"elementor elementor-2474\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-253183c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"253183c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-f2347aa\" data-id=\"f2347aa\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-7dbf515 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7dbf515\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-5c2a65a\" data-id=\"5c2a65a\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9f8b697 elementor-widget elementor-widget-heading\" data-id=\"9f8b697\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">New publication: Chitosan\/dialdehyde cellulose hydrogels with covalently anchored polypyrrole: Novel conductive, antibacterial, antioxidant, immunomodulatory, and anti-inflammatory materials\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2d0f4fd elementor-widget elementor-widget-text-editor\" data-id=\"2d0f4fd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Our colleague Doctor Ond\u0159ej Va\u0161\u00ed\u010dek has published a new paper in cooperation with Doctor Jan V\u00edcha and Professor Petr Humpol\u00ed\u010dek from Tom\u00e1\u0161 Ba\u0165a University in Zl\u00edn.<\/p><p>In this work, conductive composite hydrogels with covalently attached polypyrrole (PPy) nanoparticles were prepared. These hydrogels are based on partially re-acetylated chitosan, which is soluble at physiological pH, simplifying synthesis and purification. Low-toxic dialdehyde cellulose (DAC) was used for crosslinking chitosan and anchoring PPy particles. This is the first report of the condensation reaction between DAC and PPy, which improves PPy anchoring and control over the composite&#8217;s properties. The combination of chitosan and PPy enhances the biological properties of the hydrogels, making them non-cytotoxic, non-irritating, antibacterial, and capable of capturing reactive oxygen species. They also have conductivity similar to human tissues, promote in vitro cell growth, and have immunomodulatory effects. The covalent attachment of PPy strengthens the hydrogel network, presenting a promising method for developing advanced biomaterials.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-69b243b elementor-button-success elementor-align-center elementor-widget elementor-widget-button\" data-id=\"69b243b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-lg\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0144861723011050?via%3Dihub\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Full text of the article<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-c6ca730 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c6ca730\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-5a6587e\" data-id=\"5a6587e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b8e39c4 elementor-widget elementor-widget-image\" data-id=\"b8e39c4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"768\" height=\"316\" src=\"https:\/\/dbis.ibp.cz\/wp-content\/uploads\/2024\/05\/grafic_abstract_2-768x316.jpg\" class=\"attachment-medium_large size-medium_large wp-image-2478\" alt=\"\" srcset=\"https:\/\/dbis.ibp.cz\/wp-content\/uploads\/2024\/05\/grafic_abstract_2-768x316.jpg 768w, https:\/\/dbis.ibp.cz\/wp-content\/uploads\/2024\/05\/grafic_abstract_2-300x124.jpg 300w, https:\/\/dbis.ibp.cz\/wp-content\/uploads\/2024\/05\/grafic_abstract_2-1024x422.jpg 1024w, https:\/\/dbis.ibp.cz\/wp-content\/uploads\/2024\/05\/grafic_abstract_2-1536x632.jpg 1536w, https:\/\/dbis.ibp.cz\/wp-content\/uploads\/2024\/05\/grafic_abstract_2-2048x843.jpg 2048w\" sizes=\"(max-width: 768px) 100vw, 768px\" title=\"\">\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">Graphical abstract<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>New publication: Chitosan\/dialdehyde cellulose hydrogels with covalently anchored polypyrrole: Novel conductive, antibacterial, antioxidant, immunomodulatory, and anti-inflammatory materials Our colleague Doctor Ond\u0159ej Va\u0161\u00ed\u010dek has published a new paper in cooperation with Doctor Jan V\u00edcha and Professor Petr Humpol\u00ed\u010dek from Tom\u00e1\u0161 Ba\u0165a University in Zl\u00edn. In this work, conductive composite hydrogels with covalently attached polypyrrole (PPy) nanoparticles [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":2466,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[127],"tags":[],"class_list":["post-2474","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-new-publication","entry","has-media"],"_links":{"self":[{"href":"https:\/\/dbis.ibp.cz\/index.php\/wp-json\/wp\/v2\/posts\/2474","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dbis.ibp.cz\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dbis.ibp.cz\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dbis.ibp.cz\/index.php\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/dbis.ibp.cz\/index.php\/wp-json\/wp\/v2\/comments?post=2474"}],"version-history":[{"count":10,"href":"https:\/\/dbis.ibp.cz\/index.php\/wp-json\/wp\/v2\/posts\/2474\/revisions"}],"predecessor-version":[{"id":2603,"href":"https:\/\/dbis.ibp.cz\/index.php\/wp-json\/wp\/v2\/posts\/2474\/revisions\/2603"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dbis.ibp.cz\/index.php\/wp-json\/wp\/v2\/media\/2466"}],"wp:attachment":[{"href":"https:\/\/dbis.ibp.cz\/index.php\/wp-json\/wp\/v2\/media?parent=2474"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dbis.ibp.cz\/index.php\/wp-json\/wp\/v2\/categories?post=2474"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dbis.ibp.cz\/index.php\/wp-json\/wp\/v2\/tags?post=2474"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}