The Department of Biophysics of Immune System (DBIS) under Biophysics of the Czech Academy of Science (IBP CAS) is focused on the evaluation of molecular mechanisms responsible for the pathological deregulation of the immune system response, including inflammation, infection and tissue injury.
Deregulation of immune response is the underlying cause precipitating the development of a wide range of pathologies such as cardiovascular diseases, inflammatory bowel disease, rheumatoid arthritis, and many others. Therefore, improving understanding of the molecular mechanisms involved in the development of these pathological processes and the effects of external factors that cause deregulation of these mechanisms will lead to development of new therapeutic strategies to treat these maladies.