Publications

2026

Copper(II) complexes of indolo[2,3-c]quinoline-derived Schiff bases: Insight into the mechanism of their antiproliferative activity

Published: 2026, European Journal of Medicinal Chemistry

DOI: 10.1016/j.ejmech.2026.118882.

Hyaluronan exerts unique microbiome and metabolic effects compared with pectin: a multi-omics study of dietary polysaccharidess

Romana Šínová, Kristýna Turková, Matěj Šimek, Vratislav Berka, Tereza Foglová, Martin Šindelář, Martin Schwarzer, Kristina Nešporová, Lukáš Kubala

Published: 2026, International Journal of Biological Macromolecules

DOI: 10.1016/j.ijbiomac.2026.153043

Simultaneous Cross-Linking and Nanoparticle Anchoring by Dialdehyde Cellulose in Injectable Composite Chitosan/Polypyrrole Hydrogels

Monika Muchová, Lukáš Münster, Roman Kolařík, Zdenka Víchová, Ondřej Vašíček, Petr Humpolíček, Jan Vícha

Published: 2026, ACS Applied Bio Materials

DOI: 10.1021/acsabm.5c02494

Intravenous Administration of Hyaluronan in Veterinary Musculoskeletal Disorders: Therapeutic Applications and Mechanisms

Daniela Rubanová, Kristina Nešporová, Lukáš Kubala

Published: 2026, International Journal of Veterinary Science and Medicine

DOI: 10.4103/IJVSM.IJVSM_2_25.

Gassericins from Lactobacillus Paragasseri K7: Preparative Isolation and Discovery of Dose-Dependent Anti-Inflammatory Effects

Humna Liaqat, Diana Paveljšek, Jernej Oberčkal, Gabriela Ambrožová, Kristýna Turková, Lukáš Kubala, Adrijana Leonardi, Igor Križaj, Bojana Bogovič Matijašić

Published: 2026, Probiotics and antimicrobial proteins

DOI: 10.1007/s12602-025-10910-x

Revisiting Hyaluronan Catabolism in Bacteroides: Pathway Conservation, Overlooked Proteins, and Predictive Accuracy

Martin Sindelar, Anna Kocurkova, Matej Simek, Pavel Roudnicky, Gabriela Ambrozova, Lukas Kubala, Kristyna Turkova

Published: 2026, Microbiologyopen

DOI: 10.1002/mbo3.70227

2025

Novel Insights into Systemic Hyaluronic Acid Therapy in Dogs with Osteoarthritis from an Exploratory Postmarketing Study: Clinical Improvements Linked to Biomarker Changes

Jana Matonohová, Matěj Šimek, Vratislav Berka, Lucie Bystroňová, Iva Lžičařová, Daniela Rubanová, Lukáš Kubala, Vladimír Velebný Kristina Nešporová

Published: 2025, Animals (Basel)

DOI: 10.3390/ani15213140

Role of hyaluronan in endometrial receptivity: key insights for implantation and reproductive success

Eva Krivakova, Michal Michna, Nicole Fabianova, Maria Marekova, Silvia Toporcerova, Lukas Kubala, Miroslava Rabajdova

Published: 2025, Reprod Biol Endocrinol.

DOI: 10.1186/s12958-025-01452-6

Cholesterol Derivatives Regulate Adenylyl Cyclase 7 Activity by Binding CARC and CRAC Motifs in the Cytosolic Subunits

Radim Jaroušek, Petra Dad’ová, Alexandra Litvinchuk, Leticia Dobler, Lukáš Kubala

Published: 2025, ACS Omega

DOI: 10.1021/acsomega.5c00741

Uncovering pre-cytokinetic block in cancer cells under shear stress using a disturbed flow-generating device

Lucie Beresova, Jan Vitecek, Iva Protivánková, Michal Dudka, Katarina Chroma, Zdenek Skrott, Tereza Buchtova, Kamila Poláková, Jan Novotny, Ludmila Novakova, Jiri Bartek, Martin Mistrik

Published: 2025, Scientific reports

DOI: 10.1038/s41598-024-83058-3

One-step fabrication of chitosan/dialdehyde cellulose/polypyrrole composite nanofibers with antibacterial, antioxidant, and immunomodulatory effects

Monika Muchová, Lukáš Münster , Kristýna Valášková, Lenka Lovecká, Zdenka Víchová, Josef Osička, Věra Kašpárková, Petr Humpolíček, Ondřej Vašíček, Jan Vícha

Published: 2025, International journal of biological macromolecules

DOI: 10.1016/j.ijbiomac.2025.142105

Role of hyaluronan in endometrial receptivity: key insights for implantation and reproductive success

Eva Krivakova, Michal Michna, Nicole Fabianova, Maria Marekova, Silvia Toporcerova, Lukas Kubala, Miroslava Rabajdova

Published: 2025, Reproductive biology and endocrinology

DOI: 10.1186/s12958-025-01452-6

Alleviating UV-induced photoaging with oral hyaluronic acid: insights from a hairless mouse model

Matěj Šimek, Romana Šínová, Vratislav Berka, Kateřina Lehká, Kristina Nešporová, Iva Dolečková, Martina Bajerová, Vojtěch Pavlík, Lukáš Kubala

Published: 2025, International journal of biological macromoles

DOI: 10.1016/j.ijbiomac.2025.146340

Pharmacokinetics of the systemic application of hyaluronic acid for joint arthritis treatment

Matěj Šimek, Daniela Rubanová, Kristina Nešporová, Svitlana Skoroplyas, Kateřina Lehká, Petra Raptová, Vladimír Velebný, Lukáš Kubala

Published: 2025, International journal of biological macromoles

DOI: 10.1016/j.ijbiomac.2025.141937

Decoding structural determinants of aryl hydrocarbon receptor antagonism by monoterpenoids

Iveta Zůvalová, Barbora Vyhlídalová, Karolína Ondrová, Petr Nádvorník, Jiří Hrubý, Peter Illés, Miroslav Soural, Marek Šebela, Lenka Šindlerová, Lukáš Kubala, Sridhar Mani, Zdeněk Dvořák

Published: 2025, Bioorganic chemistry

DOI: 10.1016/j.bioorg.2025.108265

Polymer nanotherapeutics with the controlled release of acetylsalicylic acid and its derivatives inhibiting cyclooxygenase isoforms and reducing the production of pro-inflammatory mediators

Markéta Frejková, Kateřina Běhalová, Daniela Rubanová, Juan Bautista De Sanctis, Lukáš Kubala, Petr Chytil, Alice Šimonová, Tomáš Křížek, Eva Randárová, Kristýna Gunár, Tomáš Etrych

Published: 2024, International journal of pharmaceutics

DOI: 10.1016/j.ijpharm.2024.124742

Unexpectedly Regioselective Diels-Alder Reactions of New Unsymmetrical Benzoquinones: A Convenient Synthetic Entry to Uniquely Substituted Decalins